News from the NNI Community - Research Advances Funded by Agencies Participating in the NNI

Date Published

Researchers at Rice University have demonstrated that spheres made of bismuth, oxygen, and carbon wrapped with nitrogen-doped graphene oxide can inactivate multidrug-resistant Escherichia coli bacteria and degrade antibiotic-resistant genes in secondary wastewater effluent.

(Funded by the National Science Foundation)

Researchers at Rice University have demonstrated that spheres made of bismuth, oxygen, and carbon wrapped with nitrogen-doped graphene oxide can inactivate multidrug-resistant Escherichia coli bacteria and degrade antibiotic-resistant genes in secondary wastewater effluent.

(Funded by the National Institutes of Health and the National Science Foundation)

Biomedical engineers at Duke University have devised a method that uses nanoparticles called gold nanostars to simultaneously detect the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification. The technique could be used to identify early biomarkers of cancer and other diseases without the need for the elaborate, time-consuming, and expensive processes required by current technologies.

(Funded by the National Institutes of Health and the National Science Foundation)

Biomedical engineers at Duke University have devised a method that uses nanoparticles called gold nanostars to simultaneously detect the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification. The technique could be used to identify early biomarkers of cancer and other diseases without the need for the elaborate, time-consuming, and expensive processes required by current technologies.

(Funded by the U.S. Department of Defense, the National Science Foundation and the National Institutes of Health)

Researchers at MIT and elsewhere have found a new method for inducing mechanical stimulation of nerve cells in the body. The finding might offer a step toward new kinds of therapeutic treatments, similar to electrically based neurostimulation that has been used to treat Parkinson's disease and other conditions. Unlike those systems, which require an external wire connection, the new system would be completely contact-free after an initial injection of nanoparticles, and could be reactivated at will through an externally applied magnetic field.

(Funded by the U.S. Department of Defense, the National Science Foundation and the National Institutes of Health)

Researchers at MIT and elsewhere have found a new method for inducing mechanical stimulation of nerve cells in the body. The finding might offer a step toward new kinds of therapeutic treatments, similar to electrically based neurostimulation that has been used to treat Parkinson's disease and other conditions. Unlike those systems, which require an external wire connection, the new system would be completely contact-free after an initial injection of nanoparticles, and could be reactivated at will through an externally applied magnetic field.

(Funded by the National Institutes of Health and the National Science Foundation)

Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice, the researchers showed that they could use this system to monitor bacterial pneumonia and a genetic disorder of the lungs called alpha-1 antitrypsin deficiency.

(Funded by the National Institutes of Health and the National Science Foundation)

Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice, the researchers showed that they could use this system to monitor bacterial pneumonia and a genetic disorder of the lungs called alpha-1 antitrypsin deficiency.

(Funded by the National Institutes of Health)

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells. Triple negative breast cancer is one of the most aggressive and fatal types of breast cancer. The researchers linked a class of nanomaterials, called metal-organic frameworks, with the ligands of an already-developed photodynamic therapy drug to create a nano-porous material that targets and kills tumor cells without creating toxicity for normal cells.

(Funded by the National Institutes of Health)

Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells. Triple negative breast cancer is one of the most aggressive and fatal types of breast cancer. The researchers linked a class of nanomaterials, called metal-organic frameworks, with the ligands of an already-developed photodynamic therapy drug to create a nano-porous material that targets and kills tumor cells without creating toxicity for normal cells.