News from the NNI Community - Research Advances Funded by Agencies Participating in the NNI

Date Published
(Funded by the U.S. Department of Agriculture, the U.S. Department of Defense, and the U.S. Department of Energy)

Engineers at Washington University in St. Louis have made a new fiber that is stronger than steel and tougher than Kevlar. A problem associated with artificial spider silk fiber is the need to create beta-nanocrystals, a main component of natural spider silk, which contributes to its strength. So, the engineers redesigned the silk sequence by introducing amyloid sequences that have a high tendency to form beta-nanocrystals.

(Funded by the National Institutes of Health and the U.S. Department of Defense)

Engineers at Washington University in St. Louis have used nanoparticles to manipulate the electrical activity of neurons in the brain and of heart muscle cells. The noninvasive technology inhibits the electrical activity of neurons using polydopamine nanoparticles and near-infrared light. The negatively charged nanoparticles, which selectively bind to neurons, absorb near-infrared light that creates heat, which is then transferred to the neurons, inhibiting their electrical activity. By contrast, when applied to heart muscle cells, the technology excited them, showing that the excitability in cells can be either increased or decreased, depending on their type.

(Funded by the National Science Foundation and the U.S. Department of Energy)

Designing new nanomaterials is an important aspect of developing next-generation devices used in electronics, sensors, energy harvesting and storage, and optical detectors. To design such nanomaterials, researchers create interatomic potentials through atomistic modeling, a computational approach that predicts how these materials behave by accounting for their properties at the smallest level. Now, researchers at Northwestern University have developed a new framework using machine learning that improves the accuracy of interatomic potentials in new materials design. The findings could lead to more accurate predictions of how new materials transfer heat, deform, and fail at the atomic scale.

(Funded by the National Science Foundation, the U.S. Department of Energy, and the U.S. Department of Defense)

Researchers have discovered a "layer" Hall effect in a solid state chip constructed of antiferromagnetic manganese bismuth telluride, a finding that signals a much sought-after topological Axion insulating state. Researchers believe that when it is fully understood, topological Axion insulators can be used to make semiconductors with potential applications in electronic devices. The material (antiferromagnetic manganese bismuth telluride) forms a two-dimensional layered crystal structure, which allowed the researchers to mechanically exfoliate atom-thick flakes using cellophane tape. Thin flake structures with even numbers of layers were proposed to be an Axion insulator.

(Funded by the U.S. Department of Energy and the National Science Foundation)

Physicists at MIT have observed signs of a rare type of superconductivity in a material called magic-angle twisted trilayer graphene. The researchers report that the material exhibits superconductivity at surprisingly high magnetic fields of up to 10 Tesla, which is three times higher than what the material is predicted to endure if it were a conventional superconductor. The results strongly imply that magic-angle trilayer graphene is a very rare type of superconductor that is impervious to high magnetic fields. Such exotic superconductors could vastly improve technologies such as magnetic resonance imaging (MRI). MRI machines are currently limited to magnet fields of 1 to 3 Tesla. 

(Funded in part by the U.S. Department of Energy)

The magnetic component of today's memory devices is typically made of magnetic thin films. But at the atomic level, these magnetic films are still three-dimensional – hundreds or thousands of atoms thick. For decades, researchers have searched for ways to make thinner and smaller 2D magnets and thus enable data to be stored at a much higher density. Now, scientists at the University of California, Berkeley, and the U.S. Department of Energy's Lawrence Berkeley National Laboratory have developed an ultrathin 2D magnet that operates at room temperature and could lead to new applications in computing and electronics – such as high-density, compact spintronic memory devices – and new tools for the study of quantum physics.

(Funded by the National Science Foundation)

For decades, researchers have searched for ways to use solar power to generate the key reaction for producing hydrogen as a clean energy source—splitting water molecules to form hydrogen and oxygen. But such efforts have mostly failed because doing it well was too costly, and trying to do it at a low cost led to poor performance. Now, researchers from The University of Texas at Austin have found a low-cost way to solve one half of the equation, using sunlight to efficiently split off oxygen molecules from water. The key to this breakthrough came through a method of creating electrically conductive paths through a thick silicon dioxide layer that involves arrays of nanoscale "spikes" of aluminum and that can be performed at low cost and scaled to high manufacturing volumes.

(Funded by the National Institutes of Health)

Most of the tests that doctors use to diagnose cancer are based on imaging. Cancer can also be found with molecular diagnostics, which can detect specific cancer-associated molecules that circulate in bodily fluids, such as blood and urine. Now, engineers at MIT have created a new diagnostic nanoparticle that combines both of these features: It can reveal the presence of cancerous proteins through a urine test, and it functions as an imaging agent, pinpointing the tumor location.

(Funded by the National Institutes of Health and the National Science Foundation)

Current biological treatments for autoimmune diseases consist of monoclonal antibodies that search out and destroy factors in the immune system, such as the tumor necrosis factor, that mistakenly mount immune attacks against the body. But these treatments often have side effects and can have varying degrees of effectiveness in different individuals. Now, engineers at Duke University have built nanostructures which chemically tether protein subunits that can stimulate the type of biological response necessary to sequester the disease-causing excess of tumor necrosis factor.

(Funded by the U.S. Department of Energy, the U.S. Department of Defense, and the National Science Foundation)

Using a pioneering imaging technique, researchers at Cornell University have obtained a high-resolution snapshot of how ligands – molecules that bind to other molecules or metals – interact with the surface of nanoparticles. In doing so, the researchers made an unexpected discovery: They determined that by varying the concentration of an individual ligand, they could control the shape of the particle to which it is attached. This approach could result in chemical sensors that are sensitive at a very low level to a specific chemical in the environment.