News from the NNI Community - Research Advances Funded by Agencies Participating in the NNI

Date Published
(Funded by the U.S. Department of Energy)

A team of scientists from the U.S. Department of Energy's Ames National Laboratory, Iowa State University, and the University at Buffalo has developed an antimicrobial spray that deposits a layer of nanowires onto high-touch surfaces in public spaces. The spray contains copper nanowires or copper-zinc nanowires and can form an antimicrobial coating on a variety of surfaces.

(Funded by the National Science Foundation and the National Institutes of Health)

An interdisciplinary team of researchers at the University of Alabama at Birmingham has developed a new process that could limit the proliferation of toxins from implants into a patient's bloodstream. A major challenge of developing nanoparticle-modified biomedical implant material is to attach metallic nanoparticles on different surfaces, because these nanoparticles tend to detach from the implant surfaces and end up in a patient’s bloodstream. To address this issue, the researchers anchored silver nanoparticles on the surface of 3D-printed polymers without any rapid release into the surroundings.

(Funded by the National Institutes of Health and the U.S. Department of Defense)

Researchers from the Massachusetts Institute of Technology, the Broad Institute of MIT and Harvard, the Whitehead Institute for Biomedical Research, and Massachusetts General Hospital have analyzed the interactions between 35 different types of nanoparticles and nearly 500 types of cancer cells, revealing thousands of biological traits that influence whether those cells take up different types of nanoparticles. The findings could help researchers better tailor their drug-delivery nanoparticles to specific types of cancer, or design new nanoparticles that take advantage of the biological features of particular types of cancer cells. 

(Funded by the U.S. Department of Defense)

Researchers at the University of Massachusetts Amherst have overcome a major challenge to isolating and detecting molecules at the same time and at the same location in microfluidic devices. The work demonstrates an important advance in using graphene for electrokinetic biosample processing and analysis and could allow lab-on-a-chip devices to become smaller and achieve results faster.

(Funded by the National Institutes of Health)

Pharmaceutical scientists at the University of Iowa have found that charged nanoparticles combined with a vaccine were effective in eliminating tumors or extending life span in mice with cancer. The nanoparticles, which were injected around melanoma tumors in mice, acted as a beacon of sorts, allowing melanoma-fighting immune cells triggered by the adenovirus vaccine to locate the tumor and overcome its defenses. 

(Funded by the U.S. Department of Defense)

In order to optimize the properties of two-dimensional (2D) materials called MXenes, researchers need to be able to arrange 2D flakes of it into three-dimensional (3D) configurations. But there is a lack of reliable manufacturing methods available today for building MXenes into 3D configurations. Now, researchers at Carnegie Mellon University are developing a nanoscale additive manufacturing technology that will enable MXenes to be dispersed in liquid and deposited, layer by layer, into stacks of 3D structures to form electrochemical and physical sensors.

(Funded in part by the U.S. Department of Defense)

Rice University scientists who "flash" materials to synthesize graphene have turned their attention to boron nitride, which is highly valued for its thermal and chemical stability. The process exposes a precursor to rapid heating and cooling to produce two-dimensional materials, in this case pure boron nitride and boron carbon nitride. The technique can be tuned to prepare purified, microscopic flakes of boron nitride, with varying degrees of carbon. Experiments with the material showed that boron nitride flakes can be used as part of a powerful anti-corrosive coating.

(Funded by the U.S. Department of Defense and the National Science Foundation)

Researchers from the University of Washington, Stanford University, the University of Maryland, MIT, and the Charles Stark Draper Laboratory in Cambridge, MA, have designed an energy-efficient, silicon-based non-volatile switch that manipulates light through the use of a phase-change material and a graphene heater. Previously, other researchers used doped silicon to heat the phase-change material, but this process is not very energy-efficient. So, in this study, the researchers used an un-doped silicon layer to propagate light and introduced a layer of graphene between the silicon and phase-change material to conduct electricity. This design eliminates wasted energy by directing all heat generated by the graphene to go toward changing the phase-change material. 

(Funded in part by the National Science Foundation, the U.S. Department of Energy, and the U.S. Department of Defense)

In 2018, MIT researchers found that if two graphene layers are stacked at a specific “magic” angle, the twisted bilayer structure could exhibit robust superconductivity. Recently, the same group found that a similar superconductive state exists in twisted trilayer graphene — a structure made from three graphene layers stacked at a precise, new magic angle. This time, researchers from MIT and the National Institute for Materials Science in Tsukuba, Japan, have found that four and five graphene layers can be twisted and stacked at new angles to elicit robust superconductivity at low temperatures. This latest discovery establishes the various twisted and stacked configurations of graphene as the first known family of multilayer magic-angle superconductors. 

(Funded by the National Science Foundation and the U.S. Department of Defense)

Researchers from the University of Texas at Dallas and Yale University have demonstrated an atomically thin, intelligent quantum sensor that can simultaneously detect all the fundamental properties of an incoming light wave. The device exploits the unique physical properties of a novel family of two-dimensional materials, called moiré metamaterials, that have periodic structures and are atomically thin – in this case, two layers of twisted bilayer graphene, for a total of four atomic layers.