Applications of Nanotechnology

After more than 20 years of basic nanoscience research and more than fifteen years of focused R&D under the NNI, applications of nanotechnology are delivering in both expected and unexpected ways on nanotechnology’s promise to benefit society.

Nanotechnology is helping to considerably improve, even revolutionize, many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. Described below is a sampling of the rapidly growing list of benefits and applications of nanotechnology.
 

Everyday Materials and Processes

Many benefits of nanotechnology depend on the fact that it is possible to tailor the structures of materials at extremely small scales to achieve specific properties, thus greatly extending the materials science toolkit. Using nanotechnology, materials can effectively be made stronger, lighter, more durable, more reactive, more sieve-like, or better electrical conductors, among many other traits. Many everyday commercial products are currently on the market and in daily use that rely on nanoscale materials and processes:

• Nanoscale additives to or surface treatments of fabrics can provide lightweight ballistic energy deflection in personal body armor, or can help them resist wrinkling, staining, and bacterial growth.
• Clear nanoscale films on eyeglasses, computer and camera displays, windows, and other surfaces can make them water- and residue-repellent, antireflective, self-cleaning, resistant to ultraviolet or infrared light, antifog, antimicrobial, scratch-resistant, or electrically conductive.
• Nanoscale materials are beginning to enable washable, durable “smart fabrics” equipped with flexible nanoscale sensors and electronics with capabilities for health monitoring, solar energy capture, and energy harvesting through movement.
• Lightweighting of cars, trucks, airplanes, boats, and space craft could lead to significant fuel savings. Nanoscale additives in polymer composite materials are being used in baseball bats, tennis rackets, bicycles, motorcycle helmets, automobile parts, luggage, and power tool housings, making them lightweight, stiff, durable, and resilient. Carbon nanotube sheets are now being produced for use in next-generation air vehicles. For example, the combination of light weight and conductivity makes them ideal for applications such as electromagnetic shielding and thermal management. 

High-resolution image of a polymer-silicate nanocomposite. This material has improved thermal, mechanical, and barrier properties and can be used in food and beverage containers, fuel storage tanks for aircraft and automobiles, and in aerospace components. (Image courtesy of NASA.)

• Nano-bioengineering of enzymes is aiming to enable conversion of cellulose from wood chips, corn stalks, unfertilized perennial grasses, etc., into ethanol for fuel. Cellulosic nanomaterials have demonstrated potential applications in a wide array of industrial sectors, including electronics, construction, packaging, food, energy, health care, automotive, and defense. Cellulosic nanomaterials are projected to be less expensive than many other nanomaterials and, among other characteristics, tout an impressive strength-to-weight ratio.
• Nano-engineered materials in automotive products include high-power rechargeable battery systems; thermoelectric materials for temperature control; tires with lower rolling resistance; high-efficiency/low-cost sensors and electronics; thin-film smart solar panels; and fuel additives for cleaner exhaust and extended range.
• Nanostructured ceramic coatings exhibit much greater toughness than conventional wear-resistant coatings for machine parts. Nanotechnology-enabled lubricants and engine oils also significantly reduce wear and tear, which can significantly extend the lifetimes of moving parts in everything from power tools to industrial machinery.
• Nanoparticles are used increasingly in catalysis to boost chemical reactions. This reduces the quantity of catalytic materials necessary to produce desired results, saving money and reducing pollutants. Two big applications are in petroleum refining and in automotive catalytic converters.
• Nano-engineered materials make superior household products such as degreasers and stain removers; environmental sensors, air purifiers, and filters; antibacterial cleansers; and specialized paints and sealing products, such a self-cleaning house paints that resist dirt and marks.
• Nanoscale materials are also being incorporated into a variety of personal care products to improve performance. Nanoscale titanium dioxide and zinc oxide have been used for years in sunscreen to provide protection from the sun while appearing invisible on the skin. 

Electronics and IT Applications

Nanotechnology has greatly contributed to major advances in computing and electronics, leading to faster, smaller, and more portable systems that can manage and store larger and larger amounts of information. These continuously evolving applications include:

• Transistors, the basic switches that enable all modern computing, have gotten smaller and smaller through nanotechnology. At the turn of the century, a typical transistor was 130 to 250 nanometers in size. In 2014, Intel created a 14 nanometer transistor, then IBM created the first seven nanometer transistor in 2015, and then Lawrence Berkeley National Lab demonstrated a one nanometer transistor in 2016!  Smaller, faster, and better transistors may mean that soon your computer’s entire memory may be stored on a single tiny chip.
• Using magnetic random access memory (MRAM), computers will be able to “boot” almost instantly. MRAM is enabled by nanometer‐scale magnetic tunnel junctions and can quickly and effectively save data during a system shutdown or enable resume‐play features.

• Ultra-high definition displays and televisions are now being sold that use quantum dots to produce more vibrant colors while being more energy efficient.

  SUNY College of Nanoscale Science and Engineering's Michael Liehr, left, and IBM's Bala Haranand display a wafer comprised of 7nm chips in a NFX clean room in Albany, New York. (Image courtesy of IBM.)

• Flexible, bendable, foldable, rollable, and stretchable electronics are reaching into various sectors and are being integrated into a variety of products, including  wearables, medical applications, aerospace applications, and the Internet of Things. Flexible electronics have been developed using, for example, semiconductor nanomembranes for applications in smartphone and e-reader displays. Other nanomaterials like graphene and cellulosic nanomaterials are being used for various types of flexible electronics to enable wearable and “tattoo” sensors, photovoltaics that can be sewn onto clothing, and electronic paper that can be rolled up. Making flat, flexible, lightweight, non-brittle, highly efficient electronics opens the door to countless smart products.   
• Other computing and electronic products include Flash memory chips for smart phones and thumb drives; ultra-responsive hearing aids; antimicrobial/antibacterial coatings on keyboards and cell phone casings; conductive inks for printed electronics for RFID/smart cards/smart packaging; and flexible displays for e-book readers.
• Nanoparticle copper suspensions have been developed as a safer, cheaper, and more reliable alternative to lead-based solder and other hazardous materials commonly used to fuse electronics in the assembly process.

Medical and Healthcare Applications 

This image shows the bamboo-like structure of nitrogen-doped carbon nanotubes for the treatment of cancer. (Courtesy of Wake Forest and the National Cancer Institute)

• Commercial applications have adapted gold nanoparticles as probes for the detection of targeted sequences of nucleic acids, and gold nanoparticles are also being clinically investigated as potential treatments for cancer and other diseases.
• Better imaging and diagnostic tools enabled by nanotechnology are paving the way for earlier diagnosis, more individualized treatment options, and better therapeutic success rates.
• Nanotechnology is being studied for both the diagnosis and treatment of atherosclerosis, or the buildup of plaque in arteries. In one technique, researchers created a nanoparticle that mimics the body’s “good” cholesterol, known as HDL (high-density lipoprotein), which helps to shrink plaque. 
• The design and engineering of advanced solid-state nanopore materials could allow for the development of novel gene sequencing technologies that enable single-molecule detection at low cost and high speed with minimal sample preparation and instrumentation.
• Nanotechnology researchers are working on a number of different therapeutics where a nanoparticle can encapsulate or otherwise help to deliver medication directly to cancer cells and minimize the risk of damage to healthy tissue. This has the potential to change the way doctors treat cancer and dramatically reduce the toxic effects of chemotherapy.
• Research in the use of nanotechnology for regenerative medicine spans several application areas, including bone and neural tissue engineering. For instance, novel materials can be engineered to mimic the crystal mineral structure of human bone or used as a restorative resin for dental applications. Researchers are looking for ways to grow complex tissues with the goal of one day growing human organs for transplant. Researchers are also studying ways to use graphene nanoribbons to help repair spinal cord injuries; preliminary research shows that neurons grow well on the conductive graphene surface.  
• Nanomedicine researchers are looking at ways that nanotechnology can improve vaccines, including vaccine delivery without the use of needles. Researchers also are working to create a universal vaccine scaffold for the annual flu vaccine that would cover more strains and require fewer resources to develop each year.